Publications

June 26, 2025

Articles Révisés par les Pairs

ALGALLAL EH, LAPLANTE I, CASALE D, NAJAFIPASHAKI S, POMERLEAU A, PAQUETTE T, SAMAHA AN. 2025. Activation of Infralimbic cortex neurons projecting to the nucleus accumbens shell suppresses discriminative stimulus-triggered relapse to cocaine seeking in rats. BioRxiv.

LECOCQ MR, MAINVILLE-BERTHIAUME A, LAPLANTE I, SAMAHA AN. 2025. Activating Group II Metabotropic Glutamate Receptors in the Basolateral Amygdala Inhibits Increases in Reward Seeking Triggered by Discriminative Stimuli in Rats. International Journal of Neuropsychopharmacology.

LECOCQ MR, NAJAFIPASHAKI S, CASALE D, LAPLANTE I, SAMAHA AN. 2025. Triggered Temptations: A New Procedure to Compare Reward-Seeking Behaviour Induced by Discriminative and Conditioned Stimuli in Rats. Psychopharmacology.

NDIAYE NA, SHAMLEH SA, CASALE D, CASTENADA-OUELLET S, LAPLANTE I, ROBINSON MJF, SAMAHA AN. 2024. Relapse after intermittent access to cocaine: Discriminative cues more effectively trigger drug seeking than do conditioned cues. Psychopharmacology.

ALGALLAL H, JACQUEMET V, SAMAHA AN. 2024. Intermittent nicotine access is as effective as continuous access in promoting nicotine seeking and taking in rats. Psychopharmacology.

ROBINSON MJF, BONMARIAGE QSA, SAMAHA AN. 2023. Unpredictable, intermittent access to sucrose or water promotes increased reward pursuit in rats. Behavioral Brain Research.

KHOO SY, SAMAHA AN. 2023. Metabotropic glutamate group II receptor activation in the ventrolateral dorsal striatum supresses incentive motivation for cocaine in rats. Psychopharmacology.

SERVONNET A, ROMPRÉ PP, SAMAHA AN. 2023. Optogenetic activation of basolateral amygdala-to-nucleus accumbens core neurons promotes Pavlovian approach responses but not instrumental pursuit of reward cues. Behavioral Brain Research.

NDIAYE NA, ALLAIN F, SAMAHA AN. 2022. D-amphetamine maintenance therapy reduces cocaine use in female rats. Psychopharmacology.

GARCEAU C, MARSAULT J, ROBINSON MJF, SAMAHA AN. 2023. Metabotropic group II glutamate receptors mediate cue-triggered increases in rewards-seeking behaviour. Psychopharmacology.

SERVONNET A, ALLAIN F, GRAVEL-COUINARD A, HERNANDEZ G, CAPORUSCIO CB, LEGRIX M, LÉVESQUE D, ROMPRÉ PP, SAMAHA AN. 2021. Dopaminergic mechanisms underlying the expression of antipsychotic-induced dopamine supersensitivity in rats. Neuropharmacology.

ROBINSON, T.E., KHOO, S.Y., FERRARIO, C.R., & SAMAHA, A.N. 2021. Studying dopamine in addiction: the cart should follow the horse. Trends in Neuroscience.

GARCEAU, C., SAMAHA, A.N., CORDAHI, T., SERVONNET, A., & KHOO, S.Y. 2021. Metabotropic group II glutamate receptors in the basolateral amygdala mediate cue-triggered increases in incentive motivation. Psychopharmacology.

SAMAHA, A.N., KHOO, S.Y., FERRARIO, C.R., & ROBINSON, T.E. 2021. Dopamine ‘ups and downs’ in addiction revisited. Trends in Neurosciences.

KHOO, S.Y., UHRIG, A., SAMAHA, A.N., & CHAUDHRI, N. 2021. Effects of dopamine receptor antagonism and amphetamine-induced psychomotor sensitization on sign- and goal-tracking after extended training. Behavioral Brain Research.

SERVONNET, A., UCHIDA, H., & SAMAHA, A.N. 2021. Continuous versus extended antipsychotic dosing in schizophrenia: Less is more. Behavioral Brain Research.

SAMAHA, A.N. 2020. Sugar now or cocaine later? Neuropsychopharmacology

MINOGIANIS, E.A., & SAMAHA, A.N. 2020. Taking Rapid and Intermittent Cocaine Infusions Enhances Both Incentive Motivation for the Drug and Cocaine-induced Gene Regulation in Corticostriatal Regions. Neuroscience.

ALLAIN, F., DELIGNAT-LAVAUD, B., BEAUDOIN, M.P., JACQUEMET, V., ROBINSON, T.E., TRUDEAU, L.E. & SAMAHA, A.N. 2020. Amphetamine maintenance therapy during intermittent cocaine self-administration in rats attenuates psychomotor and dopamine sensitization and reduces addiction-like behavior. Neuropsychopharmacology

ALLAIN, F. & SAMAHA, A.N. 2020. Cocaïne en « dents de scie ». Médecine/sciences

SERVONNET, A., HERNANDEZ, G., HAGE, C.E., ROMPRE, & SAMAHA, A.N. 2020. Optogenetic activation of the basolateral amygdala promotes both appetitive conditioning and the instrumental pursuit of reward cues. Journal of Neuroscience

ALGALLAL, H., ALLAIN, F., NDIAYE, N.A. & SAMAHA, A.N. 2020. Sex differences in cocaine self-administration behaviour under long access versus intermittent access conditions. Addiction Biology

AMATO, D., KRUYER, A., SAMAHA, A.N., & HEINZ, A. 2019. Hypofunctional Dopamine Uptake and Antipsychotic Treatment-Resistant Schizophrenia. Frontiers in Psychiatry

MINOGIANIS, E.A., SERVONNET, A., FILION, M.P., & SAMAHA, A.N. 2019. Role of the orbitofrontal cortex and the dorsal striatum in incentive motivation for cocaine. Behavioural Brain Research

SERVONNET, A., & SAMAHA, A.N. 2020. Antipsychotic-evoked dopamine supersensitivity. Neuropharmacology

KAWA, A.B., ALLAIN F., ROBINSON T.E. & SAMAHA A.N. 2019. The transition to cocaine addiction: the importance of pharmacokinetics for preclinical models. Psychopharmacology

GUEYE, A. B., ALLAIN, F., & SAMAHA, A.N. 2018. Intermittent intake of rapid cocaine injections promotes the risk of relapse and increases mesocorticolimbic BDNF levels during abstinence. Neuropsychopharmacology.

ALLAIN, F. & SAMAHA, A. N. 2019. Revisiting long-access versus short-access cocaine self-administration in rats: intermittent intake promotes addiction symptoms independent of session length. Addiction biology.

MINOGIANIS, E. A., SHAMS, W. M., MABROUK, O. S., WONG, J. T., BRAKE, W. G., KENNEDY, R. T., du SOUICH, P. & SAMAHA, A. N. 2018. Varying the rate of intravenous cocaine infusion influences the temporal dynamics of both drug and dopamine concentrations in the striatum. The European journal of neuroscience.

ALLAIN, F., BOUAYAD-GERVAIS, K. & SAMAHA, A. N. 2017. High and escalating levels of cocaine intake are dissociable from subsequent incentive motivation for the drug in rats. Psychopharmacology (Berl).

SERVONNET, A., MINOGIANIS, E. A., BOUCHARD, C., BEDARD, A. M., LEVESQUE, D., ROMPRE, P. P. & SAMAHA, A. N. 2017. Neurotensin in the nucleus accumbens reverses dopamine supersensitivity evoked by antipsychotic treatment. Neuropharmacology.

ALLAIN, F., ROBERTS, D. C., LEVESQUE, D. & SAMAHA, A. N. 2017. Intermittent intake of rapid cocaine injections promotes robust psychomotor sensitization, increased incentive motivation for the drug and mGlu2/3 receptor dysregulation. Neuropharmacology.

CHARRON, A., EL HAGE, C., SERVONNET, A. & SAMAHA, A. N. 2015. 5-HT2 receptors modulate the expression of antipsychotic-induced dopamine supersensitivity. Eur Neuropsychopharmacol.

ALLAIN, F., MINOGIANIS, E. A., ROBERTS, D. C. & SAMAHA, A. N. 2015. How fast and how often: The pharmacokinetics of drug use are decisive in addiction. Neurosci Biobehav Rev.

EL HAGE, C., BEDARD, A. M. & SAMAHA, A. N. 2015. Antipsychotic treatment leading to dopamine supersensitivity persistently alters nucleus accumbens function. Neuropharmacology.

BOUAYAD-GERVAIS, K., MINOGIANIS, E. A., LEVESQUE, D. & SAMAHA, A. N. 2014. The self-administration of rapidly delivered cocaine promotes increased motivation to take the drug: contributions of prior levels of operant responding and cocaine intake. Psychopharmacology (Berl).

SAMAHA, A. N. 2014. Can antipsychotic treatment contribute to drug addiction in schizophrenia? Prog Neuropsychopharmacol Biol Psychiatry.

MINOGIANIS, E. A., LEVESQUE, D. & SAMAHA, A. N. 2013. The speed of cocaine delivery determines the subsequent motivation to self-administer the drug. Neuropsychopharmacology.

BEDARD, A. M., MAHEUX, J., LEVESQUE, D. & SAMAHA, A. N. 2013. Prior haloperidol, but not olanzapine, exposure augments the pursuit of reward cues: implications for substance abuse in schizophrenia. Schizophr Bull.

SAMAHA, A. N., MINOGIANIS, E. A. & NACHAR, W. 2011. Cues paired with either rapid or slower self-administered cocaine injections acquire similar conditioned rewarding properties. PLoS One.

BEDARD, A. M., MAHEUX, J., LEVESQUE, D. & SAMAHA, A. N. 2011. Continuous, but not intermittent, antipsychotic drug delivery intensifies the pursuit of reward cues. Neuropsychopharmacology.

SAMAHA, A. N., RECKLESS, G. E., SEEMAN, P., DIWAN, M., NOBREGA, J. N. & KAPUR, S. 2008. Less is more: antipsychotic drug effects are greater with transient rather than continuous delivery. Biol Psychiatry.

SAMAHA, A. N., SEEMAN, P., STEWART, J., RAJABI, H. & KAPUR, S. 2007. “Breakthrough” dopamine supersensitivity during ongoing antipsychotic treatment leads to treatment failure over time. J Neurosci.

SAMAHA, A. N. & ROBINSON, T. E. 2005. Why does the rapid delivery of drugs to the brain promote addiction? Trends Pharmacol Sci.